Contact lens product

ABSTRACT

A contact lens product includes a contact lens and a buffer solution. The contact lens is immersed in the buffer solution, and the buffer solution includes a cycloplegic agent.

RELATED APPLICATIONS

The present application is a Continuation of U.S. application Ser. No.15/401,142, filed on Jan. 9, 2017, which claims priority of TaiwanApplication Serial Number 105103797, filed Feb. 4, 2016, which is hereinincorporated by reference.

BACKGROUND Technical Field

The present disclosure relates to a contact lens product. Moreparticularly, the present disclosure relates to a contact lens productwhich can prevent myopia or control a progression of myopia.

Description of Related Art

According to the data of World Health Organization (WHO), the prevalenceof myopia in all world countries is between 8% and 62%. However, surveysshow that the prevalence of myopia in teenagers and children under 18years old in Taiwan is up to 85%, which is significantly beyond othercountries. One reason is probably due to the highly developed 3Celectronic devices in recent years, which results in improper stimulusesand overuse of eyes of young children prematurely. Current researchesshow that once young children suffer early-onset myopia, the degree ofmyopia will increase with a certain speed. Current researches furthershow that the lower the age at which the myopia occurs is, the higherprobability of becoming high myopia (greater than or equal to 6.0 D)will be. A person suffering high myopia is more likely to suffer seriouscomplications, such as retinal detachment and glaucoma.

Therefore, if a controlling or moderating method can be conducted whenthe pseudomyopia is observed in the young children, the pseudomyopia canbe effectively prevented from becoming myopia, and the high myopia canbe further prevented.

The main cause of myopia is a variation of the optical structure ofeyeballs. The optical image is mainly affected by the factors, such ascornea, lens and the length of the eyeballs. As for a normal person,lights can be precisely focused on the retina thereof so as to obtain aclearly image. However, as for a person suffering myopia, lights arefocused in front of the retina thereof due to an excessive diopter(refractive myopia) or an excessive axial length of the eyeball (axialmyopia), so that a blurred image is obtained. Myopia symptoms of youngchildren can be divided into myopia and pseudomyopia, wherein the myopiaoccurs due to an excessive axial length of the eyeball and cannot becorrected. However, the pseudomyopia is a temporary symptom caused byexcessive tension of ciliary muscle and can be corrected. Clinically,there are many methods for correcting children pseudomyopia. The mainmethods include wearing orthokeratology and applying long-actingmydriatics. However, the orthokeratology may result in a highly externalpressure which makes the wearer uncomfortable. When the long-actingmydriatics are applied alone, a higher concentration dose is usuallyrequired. Accordingly, the probability of drug side effects is enhanced,too.

SUMMARY

According to one aspect of the present disclosure, a contact lensproduct includes a contact lens and a buffer solution. The contact lensis immersed in the buffer solution, and the buffer solution includes acycloplegic agent. When a weight percentage concentration of thecycloplegic agent in the buffer solution is ConA, a visible lightabsorption rate of the contact lens is Avi, a blue light absorption rateof the contact lens is Abl, and an ultraviolet light absorption rate ofthe contact lens is Auv, the following conditions are satisfied:

0%<ConA≤1%;

0%<Avi≤80%;

0%<Abl<100%; and

0%<Auv<100%.

BRIEF DESCRIPTION OF THE DRAWINGS

The present disclosure can be more fully understood by reading thefollowing detailed description of the embodiment, with reference made tothe accompanying drawings as follows:

FIG. 1 is a schematic view of a contact lens product according to oneembodiment of the present disclosure;

FIG. 2 is a schematic plan view of a contact lens in FIG. 1;

FIG. 3 is a schematic plan view of a contact lens according to anotherembodiment of the present disclosure;

FIG. 4 is a schematic plan view of a contact lens according to yetanother embodiment of the present disclosure;

FIG. 5 is a schematic plan view of a contact lens according to furtheranother embodiment of the present disclosure;

FIG. 6 shows a relationship between a radius and a diopter of a contactlens of the 1st example;

FIG. 7 shows a relationship between a radius and a diopter of a contactlens of the 2nd example;

FIG. 8 shows a relationship between a radius and a diopter of a contactlens of the 3rd example;

FIG. 9 shows a relationship between a radius and a diopter of a contactlens of the 4th example;

FIG. 10 shows a relationship between a radius and a diopter of a contactlens of the 5th example;

FIG. 11 shows a relationship between a radius and a diopter of a contactlens of the 6th example;

FIG. 12 shows a relationship between a radius and a diopter of a contactlens of the 7th example;

FIG. 13 shows a relationship between a radius and a diopter of a contactlens of the 8th example;

FIG. 14 shows a relationship between a radius and a diopter of a contactlens of the 9th example;

FIG. 15 shows a relationship between a radius and a diopter of a contactlens of the 10th example;

FIG. 16 shows a relationship between a radius and a diopter of a contactlens of the 11th example;

FIG. 17 shows a relationship between a radius and a diopter of a contactlens of the 12th example;

FIG. 18 shows a relationship between a radius and a diopter of a contactlens of the 13th example;

FIG. 19 shows visible light absorption rates of the contact lens of the1st example to 13th example and visible light absorption rates of thecontact lens of the 1st comparative example to 13th comparative example;

FIG. 20 shows blue light absorption rates of the contact lens of the 1stexample to 13th example and blue light absorption rates of the contactlens of the 1st comparative example to 13th comparative example; and

FIG. 21 shows ultraviolet light absorption rates of the contact lens ofthe 1st example to 13th example and ultraviolet light absorption ratesof the contact lens of the 1st comparative example to 13th comparativeexample.

DETAILED DESCRIPTION

FIG. 1 is a schematic view of a contact lens product 100 according toone embodiment of the present disclosure. The contact lens product 100includes a contact lens 110 and a buffer solution 120. The contact lens110 is immersed in the buffer solution 120.

The buffer solution 120 includes a cycloplegic agent. When a weightpercentage concentration of the cycloplegic agent in the buffer solution120 is ConA, the following condition is satisfied: 0%<ConA≤1%.Therefore, the concentration of the cycloplegic agent is proper, whichis favorable to relax the ciliary muscle and reduce the probability ofdrug side effects. Alternatively, the following condition can besatisfied: 0%<ConA≤0.5%. Alternatively, the following condition can besatisfied: 0%<ConA≤0.25%. Alternatively, the following condition can besatisfied: 0%<ConA≤0.1%. Alternatively, the following condition can besatisfied: 0%<ConA≤0.05%. Alternatively, the following condition can besatisfied: 0%<ConA≤0.01%. The buffer solution 120 can be prepared byproviding a basic solution, wherein the basic solution can be acommercially available solution for immersing and preserving contactlenses. Then the cycloplegic agent is added into the basic solution to apredetermined concentration, and chemical reactions do not occur betweenthe basic solution and the cycloplegic agent.

FIG. 2 is a schematic plan view of the contact lens 110 in FIG. 1. Thecontact lens 110 can be monofocal or multifocal. Furthermore, a frontsurface (its reference numeral is omitted) and a back surface (itsreference numeral is omitted) of the contact lens 110 can beindependently aspheric or spherical.

When a visible light absorption rate of the contact lens 110 is Avi, thefollowing condition is satisfied: 0%<Avi≤80%. Therefore, a portion ofthe visible lights can be absorbed so as to ease the photophobia.Alternatively, the following condition can be satisfied: 5%≤Avi≤70%.Alternatively, the following condition can be satisfied: 5%≤Avi≤60%.Alternatively, the following condition can be satisfied: 5%≤Avi≤50%.Alternatively, the following condition can be satisfied: 10%≤Avi≤50%.Alternatively, the following condition can be satisfied: 15%≤Avi≤45%.

When a blue light absorption rate of the contact lens 110 is Abl, thefollowing condition is satisfied: 0%<Abl<100%. Therefore, thehigh-energy blue lights can be absorbed, and the probability that theretina hurt by the blue lights can be reduced. Alternatively, thefollowing condition can be satisfied: 10%≤Abl≤80%. Alternatively, thefollowing condition can be satisfied: 20%≤Abl≤70%. Alternatively, thefollowing condition can be satisfied: 30%≤Abl≤70%. Alternatively, thefollowing condition can be satisfied: 40%≤Abl≤60%. Alternatively, thefollowing condition can be satisfied: 45%≤Abl≤60%.

When an ultraviolet light absorption rate of the contact lens 110 isAuv, the following condition is satisfied: 0%<Auv<100%. Therefore, thehigh-energy ultraviolet lights can be absorbed, and the probability thatthe retina hurt by the ultraviolet lights can be reduced. Alternatively,the following condition can be satisfied: 40%≤Auv<100%. Alternatively,the following condition can be satisfied: 50%≤Auv<100%. Alternatively,the following condition can be satisfied: 60%≤Auv<100%. Alternatively,the following condition can be satisfied: 70%≤Auv<100%. Alternatively,the following condition can be satisfied: 80%≤Auv<100%.

A composition for manufacturing the contact lens 110 can include atleast one light absorbing agent. The light absorbing agent can be avisible light absorbing agent or a short-wavelength light absorbingagent.

Specifically, the composition for manufacturing the contact lens 110 caninclude at least one of the visible light absorbing agent. Therefore,the contact lens 110 can absorb visible lights, which can preventexcessive visible lights entering into a wearer's eyes due to theenlarged pupil caused by the cycloplegic agent, and the photophobia canbe eased. The visible light absorbing agent can be but is not limited to1,4-bis[4-(2-methacryloxyethyl)phenylamino]anthraquinone or1,4-bis[(2-methacryloxyethyl)amino]-9,10-anthraquinone. Theaforementioned visible light absorbing agents can be used simultaneouslyor separately.

The composition for manufacturing the contact lens 110 can include atleast one of the short-wavelength light absorbing agent. Theshort-wavelength light refers to the light with a wavelength range of280 nm to 495 nm. Therefore, the contact lens 110 can absorb high-energyblue lights and/or ultraviolet lights, which can prevent excessive bluelights and/or ultraviolet lights entering into the wearer's eyes due tothe enlarged pupil caused by the cycloplegic agent, and the probabilitythat the retina hurt by the blue lights and/or ultraviolet lights can bereduced. The short-wavelength light absorbing agent can be but is notlimited to 4-(phenyldiazenyl) phenyl methacrylate or reactive yellow 15.Alternatively, the short-wavelength light absorbing agent can be but isnot limited to 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethylmethacrylate, 4-methacryloxy-2-hydroxybenzophenone, 2-phenylethylacrylate, 2-phenylethyl methacrylate, 2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole, 2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate,3-(3-(tert-butyl)-4-hydroxy-5-(5-methoxy-2H-benzo[d][1,2,3]triazol-2-yl)phenoxy)propyl methacrylate, 1,3-bis(4-benzoyl-3-hydroxyphenoxy)-2-propylmethacrylate, 1,3-bis(4-benzoyl-3-hydroxyphenoxy)-2-propanyl acrylate orN-(4-hydroxy-3-(5-methoxy-2H-benzo[d][1,2,3]triazol-2-yl)phenyl)methacrylamide.The aforementioned short-wavelength light absorbing agents can be usedsimultaneously or separately.

According to the aforementioned contact lens product 100, the contactlens 110 can be made of a silicone hydrogel. Therefore, the oxygenpermeability of the contact lens 110 can be enhanced, and the phenomena,such as red eyes, bloodshot eyes and swell, caused by the hypoxia ofcornea can be prevented. Accordingly, the long wear comfort can beprovided. The silicone hydrogel can be but is not limited to the contactlens material classified as Group V by U.S. FDA (U.S. Food and DrugAdministration), such as Balafilcon A, Comfilcon A, Efrofilcon A,Enfilcon A, Galyfilcon A, Lotrafilcon A, Lotrafilcon B, Narafilcon A,Narafilcon B, Senofilcon A, Delefilcon A and Somofilcon A.

A composition for manufacturing the silicone hydrogel can include atleast two monomers. The monomer can be 2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide, methacrylic acid,methyl methacrylate,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneor (3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide, methacrylic acid,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane,ethylene glycol dimethacrylate, 2-hydroxy-2-methyl-propiophenone andisopropyl alcohol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 0.1%to 35%, the weight percentage concentration of the N,N-dimethylacrylamide is 0.1% to 40%, the weight percentage concentration of themethacrylic acid is 0.01% to 5%, the weight percentage concentration ofthe3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneis 0.1% to 30%, the weight percentage concentration of the ethyleneglycol dimethacrylate is 0.01% to 5%, the weight percentageconcentration of the 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%,and the weight percentage concentration of the isopropyl alcohol is 0.1%to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 1% to35%, the weight percentage concentration of the N,N-dimethyl acrylamideis 1% to 20%, the weight percentage concentration of the methacrylicacid is 0.1% to 2%, the weight percentage concentration of the3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneis 1% to 30%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.1% to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, and the weightpercentage concentration of the isopropyl alcohol is 1% to 20%.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide,(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane,ethylene glycol dimethacrylate, 2-hydroxy-2-methyl-propiophenone and1-hexanol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 0.1%to 35%, the weight percentage concentration of the N,N-dimethylacrylamide is 0.1% to 40%, the weight percentage concentration of the(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane is0.1% to 40%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.01% to 5%, the weight percentage concentration ofthe 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%, and the weightpercentage concentration of the 1-hexanol is 0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 1% to35%, the weight percentage concentration of the N,N-dimethyl acrylamideis 1% to 20%, the weight percentage concentration of the(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane is 1%to 40%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.1% to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, and the weightpercentage concentration of the 1-hexanol is 1% to 30%.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide, methyl methacrylate,polysiloxane macromer, 2-hydroxy-2-methyl-propiophenone and ethanol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 0.1%to 35%, the weight percentage concentration of the N,N-dimethylacrylamide is 0.1% to 40%, the weight percentage concentration of themethyl methacrylate is 0.1% to 20%, the weight percentage concentrationof the polysiloxane macromer is 0.1% to 40%, the weight percentageconcentration of the 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%,and the weight percentage concentration of the ethanol is 0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the N-vinyl-2-pyrrolidinone is 1% to35%, the weight percentage concentration of the N,N-dimethyl acrylamideis 1% to 20%, the weight percentage concentration of the methylmethacrylate is 1% to 10%, the weight percentage concentration of thepolysiloxane macromer is 1% to 40%, the weight percentage concentrationof the 2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, and the weightpercentage concentration of the ethanol is 1% to 20%.

Each of the aforementioned compositions for manufacturing the siliconehydrogel can further include a visible light absorbing agent.Preferably, the weight percentage concentration of the visible lightabsorbing agent of the composition for manufacturing the siliconehydrogel is 0.01% to 0.5%. More preferably, the weight percentageconcentration of the visible light absorbing agent of the compositionfor manufacturing the silicone hydrogel is 0.01% to 0.25%. Each of theaforementioned compositions for manufacturing the silicone hydrogel canfurther include a short-wavelength light absorbing agent. Preferably,the weight percentage concentration of the short-wavelength lightabsorbing agent of the composition for manufacturing the siliconehydrogel is 0.01% to 10%. More preferably, the weight percentageconcentration of the short-wavelength light absorbing agent of thecomposition for manufacturing the silicone hydrogel is 0.1% to 5%.Furthermore, the composition for manufacturing the silicone hydrogel caninclude one of the visible light absorbing agent and theshort-wavelength light absorbing agent, or can include both of thevisible light absorbing agent and the short-wavelength light absorbingagent.

By adjusting the ratio of the ingredients of the composition formanufacturing the silicone hydrogel, an oxygen permeability and ahardness of the contact lens 110 can be effectively enhanced.Furthermore, the composition for manufacturing the silicone hydrogel canselectively include other ingredients according to practical needs.

According to the aforementioned contact lens product 100, the contactlens 110 can be made of a hydrogel. Therefore, the moisture, smoothnessand softness of the contact lens 110 can be maintained, and is capableof long wear. Furthermore, the foreign body sensation can be avoidedwhen wearing the contact lens 110. The hydrogel can be but is notlimited to the contact lens material classified as Group I by U.S. FDA,i.e., nonionic polymers having a low water content (less than 50 wt %),such as Helfilcon A&B, Hioxifilcon B, Mafilcon, Polymacon, Tefilcon andTetrafilcon A. Alternatively, the hydrogel can be but is not limited tothe contact lens material classified as Group II by U.S. FDA, i.e.,nonionic polymers having a high water content (greater than 50 wt %),such as Acofilcon A, Alfafilcon A, Hilafilcon B, Hioxifilcon A,Hioxifilcon B, Hioxifilcon D, Nelfilcon A, Nesofilcon A, Omafilcon A andSamfilcon A. Alternatively, the hydrogel can be but is not limited tothe contact lens material classified as Group III by U.S. FDA, i.e.,ionic polymers having a low water content (less than 50 wt %), such asDeltafilcon A. Alternatively, the hydrogel can be but is not limited tothe contact lens material classified as Group IV by U.S. FDA, i.e.,ionic polymers having a high water content (greater than 50 wt %), suchas Etafilcon A, Focofilcon A, Methafilcon A, Methafilcon B, Ocufilcon A,Ocufilcon B, Ocufilcon C, Ocufilcon D, Ocufilcon E, Phemfilcon A andVifilcon A.

A composition for manufacturing the hydrogel can include at least twomonomers. The monomer can be 2-hydroxyethyl methacrylate, methacrylicacid, glycerol monomethacrylate or N-vinyl-2-pyrrolidinone.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, methacrylic acid, ethylene glycoldimethacrylate, 1,1,1-trimethylol propane trimethacrylate,2-hydroxy-2-methyl-propiophenone and glycerol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to96%, the weight percentage concentration of the methacrylic acid is0.01% to 5%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.01% to 5%, the weight percentage concentration ofthe 1,1,1-trimethylol propane trimethacrylate is 0.01% to 5%, the weightpercentage concentration of the 2-hydroxy-2-methyl-propiophenone is0.01% to 5%, and the weight percentage concentration of the glycerol is0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 96%, the weight percentage concentration of the methacrylic acidis 0.1% to 2%, the weight percentage concentration of the ethyleneglycol dimethacrylate is 0.1% to 2%, the weight percentage concentrationof the 1,1,1-trimethylol propane trimethacrylate is 0.1% to 2%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.1% to 2%, and the weight percentage concentration of the glycerolis 1% to 20%.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, glycerol monomethacrylate, ethylene glycoldimethacrylate, 1,1,1-trimethylol propane trimethacrylate,2-hydroxy-2-methyl-propiophenone and glycerol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to94.85%, the weight percentage concentration of the glycerolmonomethacrylate is 5% to 60%, the weight percentage concentration ofthe ethylene glycol dimethacrylate is 0.01% to 5%, the weight percentageconcentration of the 1,1,1-trimethylol propane trimethacrylate is 0.01%to 5%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.01% to 5%, and the weightpercentage concentration of the glycerol is 0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 79.4%, the weight percentage concentration of the glycerolmonomethacrylate is 20% to 50%, the weight percentage concentration ofthe ethylene glycol dimethacrylate is 0.1% to 2%, the weight percentageconcentration of the 1,1,1-trimethylol propane trimethacrylate is 0.1%to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, and the weightpercentage concentration of the glycerol is 1% to 20%.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, N-vinyl-2-pyrrolidinone, ethylene glycoldimethacrylate, 2-hydroxy-2-methyl-propiophenone and glycerol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to96%, the weight percentage concentration of the N-vinyl-2-pyrrolidinoneis 0.1% to 25%, the weight percentage concentration of the ethyleneglycol dimethacrylate is 0.01% to 5%, the weight percentageconcentration of the 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%,and the weight percentage concentration of the glycerol is 0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 96%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 0.1% to 10%, the weight percentageconcentration of the ethylene glycol dimethacrylate is 0.1% to 2%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.1% to 2%, and the weight percentage concentration of the glycerolis 1% to 20%.

Each of the aforementioned compositions for manufacturing the hydrogelcan further include a visible light absorbing agent. Preferably, theweight percentage concentration of the visible light absorbing agent ofthe composition for manufacturing the hydrogel is 0.01% to 0.5%. Morepreferably, the weight percentage concentration of the visible lightabsorbing agent of the composition for manufacturing the hydrogel is0.01% to 0.25%. Each of the aforementioned compositions formanufacturing the hydrogel can further include a short-wavelength lightabsorbing agent. Preferably, the weight percentage concentration of theshort-wavelength light absorbing agent of the composition formanufacturing the hydrogel is 0.01% to 10%. More preferably, the weightpercentage concentration of the short-wavelength light absorbing agentof the composition for manufacturing the hydrogel is 0.1% to 5%.Furthermore, the composition for manufacturing the hydrogel can includeone of the visible light absorbing agent and the short-wavelength lightabsorbing agent, or can include both of the visible light absorbingagent and the short-wavelength light absorbing agent.

By adjusting the ratio of the ingredients of the composition formanufacturing the hydrogel, a water content and a softness of thecontact lens 110 can be effectively enhanced. Furthermore, thecomposition for manufacturing the hydrogel can selectively include otheringredients according to practical needs. The monomers used in thecomposition for manufacturing the hydrogel and the monomers used in thecomposition for silicone hydrogel, such as 2-hydroxyethyl methacrylate,methacrylic acid, glycerol monomethacrylate, N-vinyl-2-pyrrolidinone,3-methacryloyloxypropyltris(trimethylsilyloxy)silane, N,N-dimethylacrylamide,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane,(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane andmethyl methacrylate can be interchanged according to practical needs.

FIG. 3 is a schematic plan view of a contact lens 210 according toanother embodiment of the present disclosure. The contact lens 210includes a central region 211 and a first annular region 212. The firstannular region 212 surrounds the central region 211. A diopter of thefirst annular region 212 is different from a diopter of the centralregion 211. Therefore, the contact lens 210 is featured with multi-focusfunction, the peripheral image can be formed in front of the retina,which can moderate the increase of the axial length of the eyeball, andthe exacerbation of myopia can be prevented. According to one example ofthe present disclosure, the diopter of the central region 211 is fixed.Moreover, the first annular region 212 can concentrically surround thecentral region 211.

At least one of the central region 211 and the first annular region 212of the contact lens 210 is aspheric. Therefore, it is favorable todesign the first annular region 212 with a gradient diopter.

When a diameter of the central region 211 of the contact lens 210 isDiC, the following condition can be satisfied: 4 mm≤DiC≤10 mm.Therefore, the diameter can be flexibly adjusted according to the pupilsize of different physiological states, so that the accuracy forcorrecting myopia provided by the central region 211 can be enhanced,and the scene can be completely and clearly focused on retina.Preferably, the following condition can be satisfied: 5 mm≤DiC≤9 mm.

When an outer diameter of the first annular region 212 of the contactlens 210 is DiP1, and the following condition can be satisfied: 6mm≤DiP1≤17 mm. Therefore, the outer diameter can be flexibly adjustedaccording to the size of palpebral fissure, so that a proper comfort andfitness of the contact lens 210 can be provided, and the wearingstability of the contact lens 210 can be enhanced. Preferably, thefollowing condition can be satisfied: 7 mm≤DiP1≤15 mm.

When the diameter of the central region 211 of the contact lens 210 isDiC, and the outer diameter of the first annular region 212 of thecontact lens 210 is DiP1, the following condition can be satisfied:0.15≤DiC/DiP1<1. Therefore, the value of DiC/DiP1 is proper, which isfavorable to design the contact lens 210 according to the physiologicalstate of individual eyeball. Accordingly, it is favorable to correctmyopia.

When the diopter of the central region 211 of the contact lens 210 isPowC, the following condition can be satisfied: −6.00 D≤PowC≤−0.25 D.Therefore, a proper correction for myopia can be provided according tothe need of users. Accordingly, a clear image can be provided.

When a maximum diopter of the first annular region 212 of the contactlens 210 is PowP1, the following condition can be satisfied: −5.50D≤PowP1≤−0.50 D. Therefore, the maximal diopter of the first annularregion 212 can be properly designed, which is favorable to correctmyopia.

When the diopter of the central region 211 of the contact lens 210 isPowC, and the maximum diopter of the first annular region 212 of thecontact lens 210 is PowP1, the following condition can be satisfied:|PowC−PowP1|≤12 D. Therefore, it is favorable to correct myopia.Furthermore, the increase degree of the diopter of the first annularregion 212 can be moderated, so that the discomfort resulted from theexcessive increase degree of the diopter can be avoided. Alternatively,the following condition can be satisfied: |PowC−PowP1|≤10 D.Alternatively, the following condition can be satisfied: |PowC−PowP1|≤5D. Alternatively, the following condition can be satisfied:|PowC−PowP1|≤3 D. Alternatively, the following condition can besatisfied: |PowC−PowP1|≤2 D. Alternatively, the following condition canbe satisfied: |PowC−PowP1|≤1.5 D. Alternatively, the following conditioncan be satisfied: |PowC−PowP1|≤1 D. Alternatively, the followingcondition can be satisfied: |PowC−PowP1|≤0.5 D. Alternatively, thefollowing condition can be satisfied: |PowC−PowP1|≤0.25 D.

The other properties of the contact lens 210 can be the same as that ofthe contact lens 110, and will not be repeated herein.

FIG. 4 is a schematic plan view of a contact lens 310 according to yetanother embodiment of the present disclosure. The contact lens 310includes a central region 311, a first annular region 312 and a secondannular region 313. The central region 311, the second annular region313 and the first annular region 312 are sequentially connected from acenter of the contact lens 310 to a periphery of the contact lens 310. Adiameter of the central region 311 of the contact lens 310 is DiC. Anouter diameter of the first annular region 312 of the contact lens 310is DiP1. An outer diameter of the second annular region 313 of thecontact lens 310 is DiP2. A diopter of the second annular region 313 isdifferent from a diopter of the central region 311. Therefore, thecontact lens 310 is featured with multi-focus function, the peripheralimage can be formed in front of the retina, which can moderate theincrease of the axial length of the eyeball, and the exacerbation ofmyopia can be prevented. According to one example of the presentdisclosure, the diopter of the central region 311 is fixed. Moreover,the central region 311, the second annular region 313 and the firstannular region 312 can be concentric.

At least one of the central region 311, the first annular region 312 andthe second annular region 313 is aspheric. Therefore, it is favorable todesign the first annular region 312 and/or the second annular region 313with a gradient diopter.

When the outer diameter of the second annular region 313 of the contactlens 310 is DiP2, the following condition can be satisfied: 5 mm≤DiP2≤13mm. Therefore, the increase degree of the diopter can be moderated.Preferably, the following condition can be satisfied: 6 mm≤DiP2≤12 mm.

When the diameter of the central region 311 of the contact lens 310 isDiC, the outer diameter of the second annular region 313 of the contactlens 310 is DiP2, the following condition can be satisfied:0.2≤DiC/DiP2<1. Therefore, the increase degree of the diopter of thesecond annular region 313 can be moderated, so that the discomfortresulted from the excessive increase degree of the diopter can beavoided.

The other properties of the contact lens 310 can be the same as that ofthe contact lens 110 or the contact lens 210, and will not be repeatedherein.

FIG. 5 is a schematic plan view of a contact lens 410 according tofurther another embodiment of the present disclosure. The contact lens410 includes a central region 411, a first annular region 412, a secondannular region 413 and a third annular region 414. The central region411, the third annular region 414, the second annular region 413 and thefirst annular region 412 are sequentially connected from a center of thecontact lens 410 to a periphery of the contact lens 410. A diameter ofthe central region 411 of the contact lens 410 is DiC. An outer diameterof the first annular region 412 of the contact lens 410 is DiP1. Anouter diameter of the second annular region 413 of the contact lens 410is DiP2. An outer diameter of the third annular region 414 of thecontact lens 410 is DiP3. A diopter of the third annular region 414 isdifferent from a diopter of the central region 411. A diopter of thesecond annular region 413 is different from the diopter of the centralregion 411. A diopter of the first annular region 412 is different fromthe diopter of the central region 411. Therefore, the contact lens 410is featured with multi-focus function, the peripheral image can beformed in front of the retina, which can moderate the increase of theaxial length of the eyeball, and the exacerbation of myopia can beprevented. According to one example of the present disclosure, thediopter of the central region 411 is fixed. Moreover, the central region411, the third annular region 414, the second annular region 413 and thefirst annular region 412 can be concentric.

As shown in FIGS. 3-5, the contact lens (210, 310, 410) according to thepresent disclosure can have at least one annular region (the firstannular region (212, 312, 412), the second annular region (313, 413),the third annular region (414)) surrounding the central region (211,311, 411). The number and the diopter of the annular region can beflexibly adjusted according to the physiological state of individualeyeball, so that the effect of correcting myopia can be enhanced.Accordingly, the myopia can be effectively prevented or controlled.

1st Example

In the 1st example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region and a first annular region.The first annular region concentrically surrounds the central region. Adiopter of the first annular region is different from a diopter of thecentral region. The schematic view of the contact lens product of the1st example can refer to FIG. 1. The structure of the contact lens ofthe 1st example can refer to FIG. 3.

In the contact lens product according to the 1st example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=1.0%.

In the contact lens product according to the 1st example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, the diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, and the value of DiC,DiP1, DiC/DiP1, PowC, PowP1 and |PowC−PowP1| of the 1st example arelisted in Table 1.

TABLE 1 1st example DiC (mm) 5.00 PowC (D) −0.25 DiP1 (mm) 13.00 PowP1(D) 0.25 DiC/DiP1 0.38 |PowC − PowP1| (D) 0.50

Please refer to Table 2 and FIG. 6 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 1st example are listedin Table 2. FIG. 6 shows a relationship between the radius and thediopter of the contact lens of the 1st example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 2 and FIG. 6, the diopter of the central region is fixed, and thediopter of the first annular region is different from the diopter of thecentral region. Specifically, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 2 1st example radius (mm) diopter (D) −6.50 0.25 −6.00 0.19 −5.500.13 −5.00 0.06 −4.50 0.00 −4.00 −0.06 −3.50 −0.13 −3.00 −0.19 −2.50−0.25 −2.00 −0.25 −1.50 −0.25 −1.00 −0.25 −0.50 −0.25 0.00 −0.25 0.50−0.25 1.00 −0.25 1.50 −0.25 2.00 −0.25 2.50 −0.25 3.00 −0.19 3.50 −0.134.00 −0.06 4.50 0.00 5.00 0.06 5.50 0.13 6.00 0.19 6.50 0.25

In the 1st example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 1 st example is listed in Table3A.

TABLE 3A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 82 monomer methacrylic acid 2.2 crosslinking agent ethyleneglycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylol propane0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone 0.5diluent glycerol 13.25 visible light1,4-bis[4-(2-methacryloxyethyl)phenyl- 0.25 absorbing agentamino]anthraquinone short-wavelength light 2-(2′-hydroxy-5′- 1.2absorbing agent methacryloxyethylphenyl)-2H- benzotriazole

In the contact lens product according to the 1st example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 1st example are listed in Table 3B.

TABLE 3B 1st example Avi (%) Abl (%) Auv(%) 17.40 10.50 72.70

The visible light (with a wavelength ranging from 380 nm to 700 nm)absorption rate can be calculated by the following formula: (1−anaverage transmittance of the wavelength ranging from 380 nm to 700nm)×100%. The blue light (with a wavelength ranging from 380 nm to 495nm) absorption rate can be calculated by the following formula: (1−anaverage transmittance of the wavelength ranging from 380 nm to 495nm)×100%. The ultraviolet light (with a wavelength ranging from 280 nmto 380 nm) absorption rate can be calculated by the following formula:(1−an average transmittance of the wavelength ranging from 280 nm to 380nm)×100%. The aforementioned formulas can be applied to calculate thevisible light absorption rate, the blue light absorption rate and theultraviolet light absorption rate of the following examples andcomparative examples, and will not be repeated hereinafter.

1st Comparative Example

The main difference between the 1st comparative example and the 1stexample is the 1st comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the1st comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 1st comparativeexample is listed in Table 4A.

TABLE 4A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 83.45 monomer methacrylic acid 2.2 crosslinking agentethylene glycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylolpropane 0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone0.5 diluent glycerol 13.25

In the contact lens product according to the 1st comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 1st comparative example are listed in Table 4B.

TABLE 4B 1st comparative example Avi (%) Abl (%) Auv(%) 4.90 2.35 9.80

The other properties of the contact lens of the 1st comparative exampleare the same as that of the 1st example, and will not be repeatedherein.

2nd Example

In the 2nd example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 2nd example can refer to FIG. 1. The structure of thecontact lens of the 2nd example can refer to FIG. 4.

In the contact lens product according to the 2nd example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.75%.

In the contact lens product according to the 2nd example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, a diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 2nd example are listed in Table 5.

TABLE 5 2nd example DiC (mm) 5.00 PowC (D) −0.50 DiP1 (mm) 16.00 PowP1(D) 0.50 DiP2 (mm) 13.00 PowP2 (D) 0.50 DiC/DiP1 0.31 |PowC − PowP1| (D)1.00 DiC/DiP2 0.38

Please refer to Table 6 and FIG. 7 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 2nd example are listedin Table 6. FIG. 7 shows a relationship between the radius and thediopter of the contact lens of the 2nd example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 6 and FIG. 7, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, the diopter of the second annular region increases whenaway from the central region, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region is fixed.

TABLE 6 2nd example radius (mm) diopter (D) −8.00 0.50 −7.50 0.50 −7.000.50 −6.50 0.50 −6.00 0.38 −5.50 0.25 −5.00 0.13 −4.50 0.00 −4.00 −0.13−3.50 −0.25 −3.00 −0.38 −2.50 −0.50 −2.00 −0.50 −1.50 −0.50 −1.00 −0.50−0.50 −0.50 0.00 −0.50 0.50 −0.50 1.00 −0.50 1.50 −0.50 2.00 −0.50 2.50−0.50 3.00 −0.38 3.50 −0.25 4.00 −0.13 4.50 0.00 5.00 0.13 5.50 0.256.00 0.38 6.50 0.50 7.00 0.50 7.50 0.50 8.00 0.50

In the 2nd example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 2nd example is listed in Table 7A.

TABLE 7A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 44.8 monomer glycerol monomethacrylate 42 crosslinkingagent ethylene glycol dimethacrylate 0.6 crosslinking agent1,1,1-trimethylol propane 0.2 trimethacrylate initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 10.35 visiblelight 1,4-bis[(2-methacryloxyethyl)amino]- 0.25 absorbing agent9,10-anthraquinone short-wavelength light 2-(2′-hydroxy-5′- 1.2absorbing agent methacryloxyethylphenyl)-2H- benzotriazole

In the contact lens product according to the 2nd example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 2nd example are listed in Table 7B.

TABLE 7B 2nd example Avi (%) Abl (%) Auv (%) 25.50 16.50 75.90

2nd Comparative Example

The main difference between the 2nd comparative example and the 2ndexample is the 2nd comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the2nd comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 2nd comparativeexample is listed in Table 8A.

TABLE 8A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 46.25 monomer glycerol monomethacrylate 42 crosslinkingagent ethylene glycol dimethacrylate 0.6 crosslinking agent1,1,1-trimethylol propane 0.2 trimethacrylate initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 10.35

In the contact lens product according to the 2nd comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 2nd comparative example are listed in Table 8B.

TABLE 8B 2nd comparative example Avi (%) Abl (%) Auv(%) 4.25 2.50 8.85

The other properties of the contact lens of the 2nd comparative exampleare the same as that of the 2nd example, and will not be repeatedherein.

3rd Example

In the 3rd example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 3rd example can refer to FIG. 1. The structure of thecontact lens of the 3rd example can refer to FIG. 4.

In the contact lens product according to the 3rd example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.35%.

In the contact lens product according to the 3rd example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, a diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 3rd example are listed in Table 9.

TABLE 9 3rd example DiC (mm) 4.00 PowC (D) −1.00 DiP1 (mm) 15.00 PowP1(D) 0.25 DiP2 (mm) 6.00 PowP2 (D) −0.50 DiC/DiP1 0.27 |PowC − PowP1| (D)1.25 DiC/DiP2 0.67

Please refer to Table 10 and FIG. 8 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 3rd example are listedin Table 10. FIG. 8 shows a relationship between the radius and thediopter of the contact lens of the 3rd example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 10 and FIG. 8, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, the diopter of the second annular region increases whenaway from the central region, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 10 3rd example radius (mm) radius (mm) radius (mm) radius (mm)−7.50 0.25 0.50 −1.00 −7.00 0.17 1.00 −1.00 −6.50 0.08 1.50 −1.00 −6.000.00 2.00 −1.00 −5.50 −0.08 2.50 −0.75 −5.00 −0.17 3.00 −0.50 −4.50−0.25 3.50 −0.42 −4.00 −0.33 4.00 −0.33 −3.50 −0.42 4.50 −0.25 −3.00−0.50 5.00 −0.17 −2.50 −0.75 5.50 −0.08 −2.00 −1.00 6.00 0.00 −1.50−1.00 6.50 0.08 −1.00 −1.00 7.00 0.17 −0.50 −1.00 7.50 0.25 0.00 −1 .00

In the 3rd example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 3rd example is listed in Table11A.

TABLE 11A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 90.85 monomer N-vinyl-2-pyrrolidinone 0.5 crosslinkingagent ethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 6.2 visible light1,4-bis[(2-methacryloxyethyl)amino]- 0.25 absorbing agent9,10-anthraquinone short-wavelength light 2-(2′-hydroxy-5′- 1.00absorbing agent methacryloxyethylphenyl)-2H- benzotriazole

In the contact lens product according to the 3rd example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 3rd example are listed in Table 11B.

TABLE 11B 3rd example Avi (%) Abl (%) Auv (%) 25.50 16.50 75.90

3rd Comparative Example

The main difference between the 3rd comparative example and the 3rdexample is the 3rd comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the3rd comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 3rd comparativeexample is listed in Table 12A.

TABLE 12A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 92.10 monomer N-vinyl-2-pyrrolidinone 0.5 crosslinkingagent ethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 6.2

In the contact lens product according to the 3rd comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 3rd comparative example are listed in Table 12B.

TABLE 12B 3rd comparative example Avi (%) Abl (%) Auv (%) 4.50 3.00 5.50

4th Example

In the 4th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region and a first annular region.The first annular region concentrically surrounds the central region. Adiopter of the first annular region is different from a diopter of thecentral region. The schematic view of the contact lens product of the4th example can refer to FIG. 1. The structure of the contact lens ofthe 4th example can refer to FIG. 3.

In the contact lens product according to the 4th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.5%.

In the contact lens product according to the 4th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, the diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, and the value of DiC,DiP1, DiC/DiP1, PowC, PowP1 and |PowC−PowP1| of the 4th example arelisted in Table 13.

TABLE 13 4th example DiC (mm) 7.00 PowC (D) −1.50 DiP1 (mm) 14.00 PowP1(D) −1.00 DiC/DiP1 0.50 |PowC − PowP1| (D) 0.50

Please refer to Table 14 and FIG. 9 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 4th example are listedin Table 14. FIG. 9 shows a relationship between the radius and thediopter of the contact lens of the 4th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 14 and FIG. 9, the diopter of the central region is fixed, and thediopter of the first annular region is different from the diopter of thecentral region. Specifically, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 14 4th example radius (mm) diopter (D) −7.00 −1.00 −6.50 −1.07−6.00 −1.14 −5.50 −1.21 −5.00 −1.29 −4.50 −1.36 −4.00 −1.43 −3.50 −1.50−3.00 −1.50 −2.50 −1.50 −2.00 −1.50 −1.50 −1.50 −1.00 −1.50 −0.50 −1.500.00 −1.50 0.50 −1.50 1.00 −1.50 1.50 −1.50 2.00 −1.50 2.50 −1.50 3.00−1.50 3.50 −1.50 4.00 −1.43 4.50 −1.36 5.00 −1.29 5.50 −1.21 6.00 −1.146.50 −1.07 7.00 −1.00

In the 4th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 4th example is listed in Table15A.

TABLE 15A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 82 monomer methacrylic acid 2.2 crosslinking agent ethyleneglycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylol propane0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent glycerol 13.35 visible light 1,4-bis[4-(2- 0.25 absorbing agentmethacryloxyethyl)phenylami- no]anthraquinone short-wavelength light2-(4-benzoyl-3-hydroxyphenoxy)ethyl 1 absorbing agent acrylate

In the contact lens product according to the 4th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 4th example are listed in Table 15B.

TABLE 15B 4th example Avi (%) Abl (%) Auv(%) 17.33 10.53 72.75

4th Comparative Example

The main difference between the 4th comparative example and the 4thexample is the 4th comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the4th comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 4th comparativeexample is listed in Table 16A.

TABLE 16A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 83.25 monomer methacrylic acid 2.2 crosslinking agentethylene glycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylolpropane 0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone0.6 diluent glycerol 13.35

In the contact lens product according to the 4th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 4th comparative example are listed in Table 16B.

TABLE 16B 4th comparative example Avi (%) Abl (%) Auv (%) 7.71 7.96 8.64

5th Example

In the 5th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 5th example can refer to FIG. 1. The structure of thecontact lens of the 5th example can refer to FIG. 4.

In the contact lens product according to the 5th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.65%.

In the contact lens product according to the 5th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, a diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 5th example are listed in Table 17.

TABLE 17 5th example DiC (mm) 8.00 PowC (D) −2.00 DiP1 (mm) 15.00 PowP1(D) 0 DiP2 (mm) 11.00 PowP2 (D) 0 DiC/DiP1 0.53 |PowC − PowP1| (D) 2.00DiC/DiP2 0.73

Please refer to Table 18 and FIG. 10 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 5th example are listedin Table 18. FIG. 10 shows a relationship between the radius and thediopter of the contact lens of the 5th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 18 and FIG. 10, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, and the diopter of the second annular region increaseswhen away from the central region, the diopter of the first annularregion is greater than the diopter of the central region, and thediopter of the first annular region is fixed.

TABLE 18 5th example radius (mm) radius (mm) −7.50 0.00 −7.00 0.00 −6.500.00 −6.00 0.00 −5.50 0.00 −5.00 −0.67 −4.50 −1.33 −4.00 −2.00 −3.50−2.00 −3.00 −2.00 −2.50 −2.00 −2.00 −2.00 −1.50 −2.00 −1.00 −2.00 −0.50−2.00 0.00 −2.00 0.50 −2.00 1.00 −2.00 1.50 −2.00 2.00 −2.00 2.50 −2.003.00 −2.00 3.50 −2.00 4.00 −2.00 4.50 −1.33 5.00 −0.67 5.50 0.00 6.000.00 6.50 0.00 7.00 0.00 7.50 0.00

In the 5th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 5th example is listed in Table19A.

TABLE 19A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 45 monomer glycerol monomethacrylate 42 crosslinking agentethylene glycol dimethacrylate 0.6 crosslinking agent 1,1,1-trimethylolpropane 0.3 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone0.6 diluent glycerol 10.35 visible light1,4-bis[(2-methacryloxyethyl)amino]- 0.25 absorbing agent9,10-anthraquinone short-wavelength light2-(4-benzoyl-3-hydroxyphenoxy)ethyl 0.9 absorbing agent acrylate

In the contact lens product according to the 5th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 5th example are listed in Table 19B.

TABLE 19B 5th example Avi (%) Abl (%) Auv (%) 25.50 16.50 75.90

5th Comparative Example

The main difference between the 5th comparative example and the 5thexample is the 5th comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the5th comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 5th comparativeexample is listed in Table 20A.

TABLE 20A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 46.15 monomer glycerol monomethacrylate 42 crosslinkingagent ethylene glycol dimethacrylate 0.6 crosslinking agent1,1,1-trimethylol propane 0.3 trimethacrylate initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 10.35

In the contact lens product according to the 5th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 5th comparative example are listed in Table 20B.

TABLE 20B 5th comparative example Avi (%) Abl (%) Auv (%) 5.25 2.25 7.55

6th Example

In the 6th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region and a first annular region.The first annular region concentrically surrounds the central region. Adiopter of the first annular region is different from a diopter of thecentral region. The schematic view of the contact lens product of the6th example can refer to FIG. 1. The structure of the contact lens ofthe 6th example can refer to FIG. 3.

In the contact lens product according to the 6th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.25%.

In the contact lens product according to the 6th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, the diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, and the value of DiC,DiP1, DiC/DiP1, PowC, PowP1 and |PowC−PowP1| of the 6th example arelisted in Table 21.

TABLE 21 6th example DiC (mm) 9.00 PowC (D) −2.50 DiP1 (mm) 14.00 PowP1(D) −2.25 DiC/DiP1 0.64 |PowC − PowP1| (D) 0.25

Please refer to Table 22 and FIG. 11 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 6th example are listedin Table 22. FIG. 11 shows a relationship between the radius and thediopter of the contact lens of the 6th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 22 and FIG. 11, the diopter of the central region is fixed, andthe diopter of the first annular region is different from the diopter ofthe central region. Specifically, the diopter of the first annularregion is greater than the diopter of the central region, and thediopter of the first annular region increases when away from the centralregion.

TABLE 22 6th example radius (mm) diopter (D) −7.00 −2.25 −6.50 −2.30−6.00 −2.35 −5.50 −2.40 −5.00 −2.45 −4.50 −2.50 −4.00 −2.50 −3.50 −2.50−3.00 −2.50 −2.50 −2.50 −2.00 −2.50 −1.50 −2.50 −1.00 −2.50 −0.50 −2.500.00 −2.50 0.50 −2.50 1.00 −2.50 1.50 −2.50 2.00 −2.50 2.50 −2.50 3.00−2.50 3.50 −2.50 4.00 −2.50 4.50 −2.50 5.00 −2.45 5.50 −2.40 6.00 −2.356.50 −2.30 7.00 −2.25

In the 6th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 6th example is listed in Table23A.

TABLE 23A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 90.15 monomer N-vinyl-2-pyrrolidinone 0.8 crosslinkingagent ethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.7 diluent glycerol 6.3 visible light1,4-bis[(2-methacryloxyethyl)amino]- 0.25 absorbing agent9,10-anthraquinone short-wavelength 2-(4-benzoyl-3-hydroxyphenoxy)ethyl1.2 light absorbing acrylate agent

In the contact lens product according to the 6th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 6th example are listed in Table 23B.

TABLE 23B 6th example Avi (%) Abl (%) Auv (%) 24.43 16.50 75.89

6th Comparative Example

The main difference between the 6th comparative example and the 6thexample is the 6th comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the6th comparative example, the contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 6th comparativeexample is listed in Table 24A.

TABLE 24A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 91.6 monomer N-vinyl-2-pyrrolidinone 0.8 crosslinking agentethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.7 diluent glycerol 6.3

In the contact lens product according to the 6th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 6th comparative example are listed in Table 24B.

TABLE 24B 6th comparative example Avi (%) Abl (%) Auv (%) 8.75 10.8815.02

7th Example

In the 7th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 7th example can refer to FIG. 1. The structure of thecontact lens of the 7th example can refer to FIG. 4.

In the contact lens product according to the 7th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.13%.

In the contact lens product according to the 7th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, a diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 7th example are listed in Table 25.

TABLE 25 7th example DiC (mm) 4.00 PowC (D) −3.00 DiP1 (mm) 15.00 PowP1(D) −1.00 DiP2 (mm) 8.00 PowP2 (D) −2.00 DiC/DiP1 0.27 |PowC − PowP1|(D) 2.00 DiC/DiP2 0.50

Please refer to Table 26 and FIG. 12 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 7th example are listedin Table 26. FIG. 12 shows a relationship between the radius and thediopter of the contact lens of the 7th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 26 and FIG. 12, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, the diopter of the second annular region increases whenaway from the central region, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 26 7th example radius (mm) diopter (D) −7.50 −1.00 −7.00 −1.14−6.50 −1.29 −6.00 −1.43 −5.50 −1.57 −5.00 −1.71 −4.50 −1.86 −4.00 −2.00−3.50 −2.25 −3.00 −2.50 −2.50 −2.75 −2.00 −3.00 −1.50 −3.00 −1.00 −3.00−0.50 −3.00 0.00 −3.00 0.50 −3.00 1.00 −3.00 1.50 −3.00 2.00 −3.00 2.50−2.75 3.00 −2.50 3.50 −2.25 4.00 −2.00 4.50 −1.86 5.00 −1.71 5.50 −1.576.00 −1.43 6.50 −1.29 7.00 −1.14 7.50 −1.00

In the 7th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 7th example is listed in Table27A.

TABLE 27A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 81 monomer methacrylic acid 2.3 crosslinking agent ethyleneglycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylol propane0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent glycerol 13.5 short-wavelength 4-(phenyldiazenyl) phenyl 2.0light absorbing methacrylate agent

In the contact lens product according to the 7th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 7th example are listed in Table 27B.

TABLE 27B 7th example Avi (%) Abl (%) Auv (%) 22.22 49.81 96.23

7th Comparative Example

The main difference between the 7th comparative example and the 7thexample is the 7th comparative example in lack of the short-wavelengthlight absorbing agent. In the 7th comparative example, the contact lensis made of hydrogel. A composition for manufacturing the hydrogel of the7th comparative example is listed in Table 28A.

TABLE 28A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 83 monomer methacrylic acid 2.3 crosslinking agent ethyleneglycol dimethacrylate 0.4 crosslinking agent 1,1,1-trimethylol propane0.2 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent glycerol 13.5

In the contact lens product according to the 7th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 7th comparative example are listed in Table 28B.

TABLE 28B 7th comparative example Avi (%) Abl (%) Auv (%) 7.30 8.2113.25

8th Example

In the 8th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region and a first annular region.The first annular region concentrically surrounds the central region. Adiopter of the first annular region is different from a diopter of thecentral region. The schematic view of the contact lens product of the8th example can refer to FIG. 1. The structure of the contact lens ofthe 8th example can refer to FIG. 3.

In the contact lens product according to the 8th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.10%.

In the contact lens product according to the 8th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, the diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, and the value of DiC,DiP1, DiC/DiP1, PowC, PowP1 and |PowC−PowP1| of the 8th example arelisted in Table 29.

TABLE 29 8th example DiC (mm) 5.00 PowC (D) −3.50 DiP1 (mm) 10.00 PowP1(D) −1.75 DiC/DiP1 0.50 |PowC − PowP1| (D) 1.75

Please refer to Table 30 and FIG. 13 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 8th example are listedin Table 30. FIG. 13 shows a relationship between the radius and thediopter of the contact lens of the 8th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 30 and FIG. 13, the diopter of the central region is fixed, andthe diopter of the first annular region is different from the diopter ofthe central region. Specifically, the diopter of the first annularregion is greater than the diopter of the central region, and thediopter of the first annular region increases when away from the centralregion.

TABLE 30 8th example radius (mm) diopter (D) −5.00 −1.75 −4.50 −2.10−4.00 −2.45 −3.50 −2.80 −3.00 −3.15 −2.50 −3.50 −2.00 −3.50 −1.50 −3.50−1.00 −3.50 −0.50 −3.50 0.00 −3.50 0.50 −3.50 1.00 −3.50 1.50 −3.50 2.00−3.50 2.50 −3.50 3.00 −3.15 3.50 −2.80 4.00 −2.45 4.50 −2.10 5.00 −1.75

In the 8th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 8th example is listed in Table31A.

TABLE 31A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 44 monomer glycerol monomethacrylate 42 crosslinking agentethylene glycol dimethacrylate 0.5 crosslinking agent 1,1,1-trimethylolpropane 0.3 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone0.6 diluent glycerol 10.6 short-wavelength 4-(phenyldiazenyl) phenyl 2light absorbing methacrylate agent

In the contact lens product according to the 8th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 8th example are listed in Table 31B.

TABLE 31B 8th example Avi (%) Abl (%) Auv (%) 23.80 50.70 96.80

8th Comparative Example

The main difference between the 8th comparative example and the 8thexample is the 8th comparative example in lack of the short-wavelengthlight absorbing agent. In the 8th comparative example, the contact lensis made of hydrogel. A composition for manufacturing the hydrogel of the8th comparative example is listed in Table 32A.

TABLE 32A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 46 monomer glycerol monomethacrylate 42 crosslinking agentethylene glycol dimethacrylate 0.5 crosslinking agent 1,1,1-trimethylolpropane 0.3 trimethacrylate initiator 2-hydroxy-2-methyl-propiophenone0.6 diluent glycerol 10.6

In the contact lens product according to the 8th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 8th comparative example are listed in Table 32B.

TABLE 32B 8th comparative example Avi (%) Abl (%) Auv (%) 4.25 2.50 8.85

9th Example

In the 9th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 9th example can refer to FIG. 1. The structure of thecontact lens of the 9th example can refer to FIG. 4.

In the contact lens product according to the 9th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.08%.

In the contact lens product according to the 9th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, the diopter ofthe central region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 9th example are listed in Table 33.

TABLE 33 9th example DiC (mm) 6.00 PowC (D) −4.00 DiP1 (mm) 14.00 PowP1(D) −3.25 DiP2 (mm) 10.00 PowP2 (D) −3.75 DiC/DiP1 0.43 |PowC − PowP1|(D) 0.75 DiC/DiP2 0.60

Please refer to Table 34 and FIG. 14 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 9th example are listedin Table 34. FIG. 14 shows a relationship between the radius and thediopter of the contact lens of the 9th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 34 and FIG. 14, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, the diopter of the second annular region increases whenaway from the central region, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 34 9th example radius (mm) diopter (D) −7.00 −3.25 −6.50 −3.38−6.00 −3.50 −5.50 −3.63 −5.00 −3.75 −4.50 −3.81 −4.00 −3.88 −3.50 −3.94−3.00 −4.00 −2.50 −4.00 −2.00 −4.00 −1.50 −4.00 −1.00 −4.00 −0.50 −4.000.00 −4.00 0.50 −4.00 1.00 −4.00 1.50 −4.00 2.00 −4.00 2.50 −4.00 3.00−4.00 3.50 −3.94 4.00 −3.88 4.50 −3.81 5.00 −3.75 5.50 −3.63 6.00 −3.506.50 −3.38 7.00 −3.25

In the 9th example, the contact lens is made of hydrogel. A compositionfor manufacturing the hydrogel of the 9th example is listed in Table35A.

TABLE 35A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 89.5 monomer N-vinyl-2-pyrrolidinone 0.8 crosslinking agentethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 6.5short-wavelength 4-(phenyldiazenyl) phenyl 2 light absorbingmethacrylate agent

In the contact lens product according to the 9th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 9th example are listed in Table 35B.

TABLE 35B 9th example Avi (%) Abl (%) Auv (%) 22.30 48.60 96.60

9th Comparative Example

The main difference between the 9th comparative example and the 9thexample is the 9th comparative example in lack of the short-wavelengthlight absorbing agent. In the 9th comparative example, the contact lensis made of hydrogel. A composition for manufacturing the hydrogel of the9th comparative example is listed in Table 36A.

TABLE 36A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 91.5 monomer N-vinyl-2-pyrrolidinone 0.8 crosslinking agentethylene glycol dimethacrylate 0.6 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent glycerol 6.5

In the contact lens product according to the 9th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 9th comparative example are listed in Table 36B.

TABLE 36B 9th comparative example Avi (%) Abl (%) Auv (%) 4.50 3.00 5.50

10th Example

In the 10th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region and a first annular region.The first annular region concentrically surrounds the central region. Adiopter of the first annular region is different from a diopter of thecentral region. The schematic view of the contact lens product of the10th example can refer to FIG. 1. The structure of the contact lens ofthe 10th example can refer to FIG. 3.

In the contact lens product according to the 10th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.05%.

In the contact lens product according to the 10th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, the diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, and the value of DiC,DiP1, DiC/DiP1, PowC, PowP1 and |PowC−PowP1| of the 10th example arelisted in Table 37.

TABLE 37 10th example DiC (mm) 7.00 PowC (D) −4.50 DiP1 (mm) 12.00 PowP1(D) −3.00 DiC/DiP1 0.58 |PowC − PowP1| (D) 1.50

Please refer to Table 38 and FIG. 15 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 10th example are listedin Table 38. FIG. 15 shows a relationship between the radius and thediopter of the contact lens of the 10th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 38 and FIG. 15, the diopter of the central region is fixed, andthe diopter of the first annular region is different from the diopter ofthe central region. Specifically, the diopter of the first annularregion is greater than the diopter of the central region, and thediopter of the first annular region increases when away from the centralregion.

TABLE 38 10th example radius (mm) diopter (D) −6.00 −3.00 −5.50 −3.30−5.00 −3.60 −4.50 −3.90 −4.00 −4.20 −3.50 −4.50 −3.00 −4.50 −2.50 −4.50−2.00 −4.50 −1.50 −4.50 −1.00 −4.50 −0.50 −4.50 0.00 −4.50 0.50 −4.501.00 −4.50 1.50 −4.50 2.00 −4.50 2.50 −4.50 3.00 −4.50 3.50 −4.50 4.00−4.20 4.50 −3.90 5.00 −3.60 5.50 −3.30 6.00 −3.00

In the 10th example, the contact lens is made of silicone hydrogel. Acomposition for manufacturing the silicone hydrogel of the 10th exampleis listed in Table 39A.

TABLE 39A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 2.3 monomer 3-methacryloyloxypropyltris 28(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 20.2 monomerN,N-dimethyl acrylamide 12.3 monomer methacrylic acid 1.5 monomer3-(3-methacryloxy-2- 21.5 hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane crosslinking agent ethylene glycoldimethacrylate 0.6 initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent isopropyl alcohol 10 short-wavelength 4-(phenyldiazenyl) phenyl2 light absorbing methacrylate agent short-wavelength2-(4-benzoyl-3-hydroxyphenoxy)ethyl 1 light absorbing acrylate agent

In the contact lens product according to the 10th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 10th example are listed in Table 39B.

TABLE 39B 10th example Avi (%) Abl (%) Auv (%) 24.39 52.04 96.87

10th Comparative Example

The main difference between the 10th comparative example and the 10thexample is the 10th comparative example in lack of the short-wavelengthlight absorbing agent. In the 10th comparative example, the contact lensis made of silicone hydrogel. A composition for manufacturing thesilicone hydrogel of the 10th comparative example is listed in Table40A.

TABLE 40A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 5.3 monomer 3-methacryloyloxypropyltris 28(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 20.2 monomerN,N-dimethyl acrylamide 12.3 monomer methacrylic acid 1.5 monomer3-(3-methacryloxy-2- 21.5 hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane crosslinking agent ethylene glycoldimethacrylate 0.6 initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent isopropyl alcohol 10

In the contact lens product according to the 10th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 10th comparative example are listed in Table 40B.

TABLE 40B 10th comparative example Avi (%) Abl (%) Auv (%) 7.85 10.3119.51

11th Example

In the 11th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region and asecond annular region. The central region, the second annular region andthe first annular region are sequentially connected from a center of thecontact lens to a periphery of the contact lens and are concentric. Atleast one of the central region, the second annular region and the firstannular region is aspheric. The schematic view of the contact lensproduct of the 11th example can refer to FIG. 1. The structure of thecontact lens of the 11th example can refer to FIG. 4.

In the contact lens product according to the 11th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.03%.

In the contact lens product according to the 11th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, a diopter of thecentral region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, and the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2 and |PowC−PowP1|of the 11th example are listed in Table 41.

TABLE 41 11th example DiC (mm) 8.00 PowC (D) −5.00 DiP1 (mm) 13.00 PowP1(D) −2.75 DiP2 (mm) 10.00 PowP2 (D) −4.00 DiC/DiP1 0.62 |PowC − PowP1|(D) 2.25 DiC/DiP2 0.80

Please refer to Table 42 and FIG. 16 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 11th example are listedin Table 42. FIG. 16 shows a relationship between the radius and thediopter of the contact lens of the 11th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 42 and FIG. 16, the diopter of the central region is fixed, thediopter of the second annular region is different from the diopter ofthe central region, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the second annular region is greater than the diopter of thecentral region, the diopter of the second annular region increases whenaway from the central region, the diopter of the first annular region isgreater than the diopter of the central region, and the diopter of thefirst annular region increases when away from the central region.

TABLE 42 11th example radius (mm) diopter (D) −6.50 −2.75 −6.00 −3.17−5.50 −3.58 −5.00 −4.00 −4.50 −4.50 −4.00 −5.00 −3.50 −5.00 −3.00 −5.00−2.50 −5.00 −2.00 −5.00 −1.50 −5.00 −1.00 −5.00 −0.50 −5.00 0.00 −5.000.50 −5.00 1.00 −5.00 1.50 −5.00 2.00 −5.00 2.50 −5.00 3.00 −5.00 3.50−5.00 4.00 −5.00 4.50 −4.50 5.00 −4.00 5.50 −3.58 6.00 −3.17 6.50 −2.75

In the 11th example, the contact lens is made of silicone hydrogel. Acomposition for manufacturing the silicone hydrogel of the 11th exampleis listed in Table 43A.

TABLE 43A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 4 monomer 3-methacryloyloxypropyltris 28(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 20.5 monomerN,N-dimethyl acrylamide 12.3 monomer (3-acryloxy-2- 22hydroxypropoxypropyl)terminated polydimethylsiloxane crosslinking agentethylene glycol dimethacrylate 0.5 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent 1-hexanol 11short-wavelength 2-(4-benzoyl-3-hydroxyphenoxy)ethyl 1.1 light absorbingacrylate agent

In the contact lens product according to the 11th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 11th example are listed in Table 43B.

TABLE 43B 11th example Avi (%) Abl (%) Auv (%) 9.00 14.90 90.00

11th Comparative Example

The main difference between the 11th comparative example and the 11thexample is the 11th comparative example in lack of the short-wavelengthlight absorbing agent. In the 11th comparative example, the contact lensis made of silicone hydrogel. A composition for manufacturing thesilicone hydrogel of the 11th comparative example is listed in Table44A.

TABLE 44A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 5.1 monomer 3-methacryloyloxypropyltris 28(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 20.5 monomerN,N-dimethyl acrylamide 12.3 monomer (3-acryloxy-2- 22hydroxypropoxypropyl)terminated polydimethylsiloxane crosslinking agentethylene glycol dimethacrylate 0.5 initiator2-hydroxy-2-methyl-propiophenone 0.6 diluent 1-hexanol 11

In the contact lens product according to the 11th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 11th comparative example are listed in Table 44B.

TABLE 44B 11th comparative example Avi (%) Abl (%) Auv (%) 7.80 9.4024.00

12th Example

In the 12th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The contact lens includes a central region, a first annular region, asecond annular region and a third annular region. The central region,the third annular region, the second annular region and the firstannular region are sequentially connected from a center of the contactlens to a periphery of the contact lens and are concentric. At least oneof the central region, the third annular region, the second annularregion and the first annular region is aspheric. The schematic view ofthe contact lens product of the 12th example can refer to FIG. 1. Thestructure of the contact lens of the 12th example can refer to FIG. 5.

In the contact lens product according to the 12th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.01%.

In the contact lens product according to the 12th example, a diameter ofthe central region of the contact lens is DiC, an outer diameter of thefirst annular region of the contact lens is DiP1, an outer diameter ofthe second annular region of the contact lens is DiP2, an outer diameterof the third annular region of the contact lens is DiP3, a diopter ofthe central region of the contact lens is PowC, a maximal diopter of thefirst annular region of the contact lens is PowP1, a maximal diopter ofthe second annular region of the contact lens is PowP2, a maximaldiopter of the third annular region of the contact lens is PowP3, andthe value of DiC, DiP1, DiP2, DiP3, DiC/DiP1, DiC/DiP2, PowC, PowP1,PowP2, PowP3 and |PowC−PowP1| of the 12th example are listed in Table45.

TABLE 45 12th example DiC (mm) 4.00 PowC (D) −5.50 DiP1 (mm) 16.00 PowP1(D) −3.00 DiP2 (mm) 12.00 PowP2 (D) −3.00 DiP3 (mm) 8.00 PowP3 (D) −3.75DiC/DiP1 0.25 |PowC − PowP1| (D) 2.50 DiC/DiP2 0.33

Please refer to Table 46 and FIG. 17 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 12th example are listedin Table 46. FIG. 17 shows a relationship between the radius and thediopter of the contact lens of the 12th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 46 and FIG. 17, the diopter of the central region is fixed, thediopter of the third annular region is different from the diopter of thecentral region, the diopter of the second annular region is differentfrom the diopter of the central region, and the diopter of the firstannular region is different from the diopter of the central region.Specifically, the diopter of the third annular region is greater thanthe diopter of the central region, the diopter of the third annularregion increases when away from the central region, the diopter of thesecond annular region is greater than the diopter of the central region,the diopter of the second annular region increases when away from thecentral region, the diopter of the first annular region is greater thanthe diopter of the central region, and the diopter of the first annularregion is fixed.

TABLE 46 12th example radius (mm) diopter (D) −8.00 −3.00 −7.50 −3.00−7.00 −3.00 −6.50 −3.00 −6.00 −3.00 −5.50 −3.19 −5.00 −3.38 −4.50 −3.56−4.00 −3.75 −3.50 −4.19 −3.00 −4.63 −2.50 −5.06 −2.00 −5.50 −1.50 −5.50−1.00 −5.50 −0.50 −5.50 0.00 −5.50 0.50 −5.50 1.00 −5.50 1.50 −5.50 2.00−5.50 2.50 −5.06 3.00 −4.63 3.50 −4.19 4.00 −3.75 4.50 −3.56 5.00 −3.385.50 −3.19 6.00 −3.00 6.50 −3.00 7.00 −3.00 7.50 −3.00 8.00 −3.00

In the 12th example, the contact lens is made of silicone hydrogel. Acomposition for manufacturing the silicone hydrogel of the 12th exampleis listed in Table 47A.

TABLE 47A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 4.2 monomer 3-methacryloyloxypropyltris 24.1(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 19.99 monomerN,N-dimethyl acrylamide 11.00 monomer methyl methacrylate 4.2 oligomerpolysiloxane macromer 25 initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent ethanol 10 visible light 1,4-bis[(2-methacryloxyethyl)amino]-0.01 absorbing agent 9,10-anthraquinone short-wavelength2-(4-benzoyl-3-hydroxyphenoxy)ethyl 0.9 light absorbing acrylate agent

In the contact lens product according to the 12th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 12th example are listed in Table 47B.

TABLE 47B 12th example Avi (%) Abl (%) Auv (%) 9.70 12.40 89.20

12th Comparative Example

The main difference between the 12th comparative example and the 12thexample is the 12th comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the12th comparative example, the contact lens is made of silicone hydrogel.A composition for manufacturing the silicone hydrogel of the 12thcomparative example is listed in Table 48A.

TABLE 48A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 5.11 monomer 3-methacryloyloxypropyltris 24.1(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 19.99 monomerN,N-dimethyl acrylamide 11.00 monomer methyl methacrylate 4.2 oligomerpolysiloxane macromer 25 initiator 2-hydroxy-2-methyl-propiophenone 0.6diluent ethanol 10

In the contact lens product according to the 12th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 12th comparative example are listed in Table 48B.

TABLE 48B 12th comparative example Avi (%) Abl (%) Auv (%) 6.37 7.4024.20

13th Example

In the 13th example, a contact lens product (not shown) includes acontact lens and a buffer solution. The contact lens is immersed in thebuffer solution, and the buffer solution includes a cycloplegic agent.The schematic view of the contact lens product of the 13th example canrefer to FIG. 1. The structure of the contact lens of the 13th examplecan refer to FIG. 2.

In the contact lens product according to the 13th example, when a weightpercentage concentration of the cycloplegic agent in the buffer solutionis ConA, the following condition is satisfied: ConA=0.18%.

In the contact lens product according to the 13th example, a diameter ofthe contact lens is 5 mm, a diopter of the contact lens is −3.50D.

Please refer to Table 49 and FIG. 18 simultaneously. The radius and thecorrespondent diopter of the contact lens of the 13th example are listedin Table 49. FIG. 18 shows a relationship between the radius and thediopter of the contact lens of the 13th example (the negative radiushaving an opposite direction with the positive radius). As shown inTable 49 and FIG. 18, the diopter of the contact lens is fixed.

TABLE 49 13th example radius (mm) diopter (D) −2.50 −3.50 −2.00 −3.50−1.50 −3.50 −1.00 −3.50 −0.50 −3.50 0.00 −3.50 0.50 −3.50 1.00 −3.501.50 −3.50 2.00 −3.50 2.50 −3.50

In the 13th example, the contact lens is made of silicone hydrogel. Acomposition for manufacturing the silicone hydrogel of the 13th exampleis listed in Table 50A.

TABLE 50A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 3.5 monomer 3-methacryloyloxypropyltris 26.00(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 19.50 monomerN,N-dimethyl acrylamide 11.10 monomer methyl methacrylate 4.10 oligomerpolysiloxane macromer 24.50 initiator 2-hydroxy-2-methyl-propiophenone1.00 diluent ethanol 9.00 visible light1,4-bis[(2-methacryloxyethyl)amino]- 0.30 absorbing agent9,10-anthraquinone short-wavelength 2-(4-benzoyl-3-hydroxyphenoxy)ethyl1.00 light absorbing acrylate agent

In the contact lens product according to the 13th example, a visiblelight absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 13th example are listed in Table 50B.

TABLE 50B 13th example Avi (%) Abl (%) Auv (%) 29.30 24.70 89.70

13th Comparative Example

The main difference between the 13th comparative example and the 13thexample is the 13th comparative example in lack of the visible lightabsorbing agent and the short-wavelength light absorbing agent. In the13th comparative example, the contact lens is made of silicone hydrogel.A composition for manufacturing the silicone hydrogel of the 13thcomparative example is listed in Table 51A.

TABLE 51A Content function Ingredient (wt %) monomer 2-hydroxyethylmethacrylate 4.8 monomer 3-methacryloyloxypropyltris 26.00(trimethylsilyloxy)silane monomer N-vinyl-2-pyrrolidinone 19.50 monomerN,N-dimethyl acrylamide 11.10 monomer methyl methacrylate 4.10 oligomerpolysiloxane macromer 24.50 initiator 2-hydroxy-2-methyl-propiophenone1.00 diluent ethanol 9.00

In the contact lens product according to the 13th comparative example, avisible light absorption rate of the contact lens is Avi, a blue lightabsorption rate of the contact lens is Abl, an ultraviolet lightabsorption rate of the contact lens is Auv, and the value of Avi, Abland Auv of the 13th comparative example are listed in Table 51B.

TABLE 51B 13th comparative example Avi (%) Abl (%) Auv (%) 6.37 7.4024.20

FIG. 19 shows the visible light absorption rates of the contact lens ofthe 1st example to 13th example and the visible light absorption ratesof the contact lens of the 1st comparative example to 13th comparativeexample. As shown in FIG. 19, the visible light absorption rate of thecontact lens of each of the 1st example to 13th example is higher thanthat of the correspondent comparative example thereof. It is obviousthat the contact lens according to the present disclosure can ease thephotophobia.

FIG. 20 shows the blue light absorption rates of the contact lens of the1 st example to 13th example and the blue light absorption rates of thecontact lens of the 1st comparative example to 13th comparative example.As shown in FIG. 20, the blue light absorption rate of the contact lensof each of the 1st example to 13th example is higher than that of thecorrespondent comparative example thereof. It is obvious that thecontact lens according to the present disclosure can reduce theprobability that the retina hurt by the blue lights.

FIG. 21 shows the ultraviolet light absorption rates of the contact lensof the 1st example to 13th example and the ultraviolet light absorptionrates of the contact lens of the 1st comparative example to 13thcomparative example. As shown in FIG. 21, the ultraviolet lightabsorption rate of the contact lens of each of the 1st example to 13thexample is higher than that of the correspondent comparative examplethereof. It is obvious that the contact lens according to the presentdisclosure can reduce the probability that the retina hurt by theultraviolet lights.

According to the contact lens of the present disclosure, an asphericsurface refers to a curved shape of a front surface or a back surfaceshown in a cross-sectional view taken along the central line of thecontact lens. The front surface is a surface of the contact lens faraway from the cornea, and the back surface is a surface of the contactlens close to the cornea.

According to the contact lens of the present disclosure, the diopter isrepresented by D. When the contact lens is for correcting myopia, thediopter thereof is negative; when the contact lens is for correctinghyperopia, the diopter thereof is positive.

According to the present disclosure, the cycloplegic agent can includebut is not limited to atropine((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate), tropicamide(N-ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide),cyclopentolate (2-(dimethylamino)ethyl(1-hydroxycyclopentyl)(phenyl)acetate), homatropine((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate),scopolamine((1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^(2,4)]non-7-yl(2S)-3-hydroxy-2-phenylpropanoate),eucatropine (1,2,2,6-tetramethyl-4-piperidinyl hydroxy(phenyl)acetate)or the salt thereof. The cycloplegic agent, also known as a mydriaticagent, belongs to a parasympathetic blocker, i.e., a non-selectivem-type muscarinic receptor blocker, which can control the paralysis andrelaxation of the ciliary muscle of pupils by blocking the muscarinicreceptor so as to enlarge the pupil.

It will be apparent to those skilled in the art that variousmodifications and variations can be made to the structure of the presentdisclosure without departing from the scope or spirit of the disclosure.In view of the foregoing, it is intended that the present disclosurecover modifications and variations of this disclosure provided they fallwithin the scope of the following claims.

What is claimed is:
 1. A contact lens product, comprising: a contactlens; and a buffer solution, wherein the contact lens is immersed in thebuffer solution, and the buffer solution comprises a cycloplegic agent;wherein a weight percentage concentration of the cycloplegic agent inthe buffer solution is ConA, a visible light absorption rate of thecontact lens is Avi, a blue light absorption rate of the contact lens isAbl, and the following conditions are satisfied: 0.01%≤ConA; 0%<Avi≤45%;and 10%≤Abl≤70%.
 2. The contact lens product of claim 1, wherein theweight percentage concentration of the cycloplegic agent in the buffersolution is ConA, and the following condition is satisfied:0.01%≤ConA<0.5%.
 3. The contact lens product of claim 1, wherein thevisible light absorption rate of the contact lens is Avi, and thefollowing condition is satisfied: 15%≤Avi≤25.5%.
 4. The contact lensproduct of claim 3, wherein a composition for manufacturing the contactlens comprises at least one visible light absorbing agent, and thevisible light absorbing agent is1,4-bis[4-(2-methacryloxyethyl)phenylamino]anthraquinone or1,4-bis[(2-methacryloxyethyl)amino]-9,10-anthraquinone.
 5. The contactlens product of claim 1, wherein the contact lens is made of a siliconehydrogel.
 6. The contact lens product of claim 5, wherein a compositionfor manufacturing the silicone hydrogel comprises at least two monomers,the monomer is 2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,N-vinyl-2-pyrrolidinone, N,N-dimethyl acrylamide, methacrylic acid,methyl methacrylate,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneor (3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane.7. The contact lens product of claim 1, wherein the contact lens is madeof a hydrogel.
 8. The contact lens product of claim 7, wherein acomposition for manufacturing the hydrogel comprises at least twomonomers, the monomer is 2-hydroxyethyl methacrylate, methacrylic acid,glycerol monomethacrylate or N-vinyl-2-pyrrolidinone.
 9. The contactlens product of claim 1, wherein a composition for manufacturing thecontact lens comprises at least one short-wavelength light absorbingagent, the blue light absorption rate of the contact lens is Abl, andthe following condition is satisfied: 40%≤Abl≤60%.
 10. The contact lensproduct of claim 9, wherein the short-wavelength light absorbing agentis 4-(phenyldiazenyl) phenyl methacrylate or reactive yellow
 15. 11. Thecontact lens product of claim 10, wherein the ultraviolet lightabsorption rate of the contact lens is Auv, and the following conditionis satisfied: 72.7%≤Auv≤96.8%.
 12. The contact lens product of claim 11,wherein the short-wavelength light absorbing agent is2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole,2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate,3-(3-(tert-butyl)-4-hydroxy-5-(5-methoxy-2H-benzo[d][1,2,3]triazol-2-yl)phenoxy)propyl methacrylate, 1,3-bis(4-benzoyl-3-hydroxyphenoxy)-2-propylmethacrylate, 1,3-bis(4-benzoyl-3-hydroxyphenoxy)-2-propanyl acrylate orN-(4-hydroxy-3-(5-methoxy-2H-benzo[d][1,2,3]triazol-2-yl)phenyl)methacrylamide.13. The contact lens product of claim 1, wherein the contact lenscomprises: a central region; and at least one annular region surroundingthe central region, wherein a diopter of the annular region is differentfrom a diopter of the central region, the annular region is a firstannular region, the diopter of the central region of the contact lens isPowC, a maximum diopter of the first annular region of the contact lensis PowP1, and the following condition is satisfied: 2.25 D≤PowP1−PowC.14. The contact lens product of claim 13, wherein the diopter of thecentral region of the contact lens is PowC, the maximum diopter of thefirst annular region of the contact lens is PowP1, and the followingcondition is satisfied: 2.25 D≤PowP1−PowC≤12 D.
 15. The contact lensproduct of claim 14, wherein a diameter of the central region of thecontact lens is DiC, and the following condition is satisfied: 4mm≤DiC≤8 mm.
 16. The contact lens product of claim 15, wherein an outerdiameter of the first annular region of the contact lens is DiP1, andthe following condition is satisfied: 6 mm≤DiP1≤16 mm.
 17. The contactlens product of claim 16, wherein the diameter of the central region ofthe contact lens is DiC, the outer diameter of the first annular regionof the contact lens is DiP1, and the following condition is satisfied:0.27≤DiC/DiP1≤0.64.